Liu loosens CO from renewable thiocarbonate platform
Citation: Rajabimoghadam, K.; Faialaga, N.H.; Naito, N.; Li, Y.; Liu, R.Y. Photochemical CO Release from a Bench-Stable, Recyclable Organic Platform: Applications to Carbonylative Cross-Coupling. Org. Lett. 2025 , ASAP. Summary figure: Background: Carbonylation reactions are really nice 3 component reactions that usually form ketones. I've posted about one of them previously (https://alwaysbecoupling.blogspot.com/2025/03/palladium-promotes-precise-conversions.html) if you want to see an example. The general idea is you can do migratory addition with a metal carbonyl to form a C-C bond, and then eventually reductively eliminate from the metal acyl complex to form another C-C bond. Usually, there are two difficulties. First, you have to get the relative rates right, or else you can directly couple your R groups. This is also a common issue with other three-component coupling reactions like dicarbofunctionalizations. Second, y...