Cross-Coupling of Chlorides with Rotating Metal Rods and Magnets
Citation: Feng, X.; Li, X.; Zhang, N.; Zhang, L.; Sun, F.; Liu, H.; Zhao, Z.; Li, X. Cross-Electrophile Coupling of Aryl Chlorides with Alkyl Chlorides Using Rotating Magnetic Field and Metal Rods. J. Am. Chem. Soc. ASAP. https://doi.org/10.1021/jacs.5c00381 Summary Figure: Background: Cross-electrophile coupling (XEC) reactions require three components to work: (1) a catalyst (2) a source of electrons (3) a way to activate the reductant. The catalyst is fairly self explanatory. Because XEC reactions are overall reductive transformations, there must be some ultimate place to get the electrons from. This can be metal powders, electrochemical metal anodes, organic reductants like (Bpin)2 or TDAE, amines, silanes, organometallic reagents, or many other reagents. Finally, there must be a way to get the electrons from the reductant to the catalyst and therefore the substrates. A lot of the divisions in the field are sorted based on the techniques used to activate t...